Invitrogen™ Human SARS2 (aa 104-177) Control Fragment Recombinant Protein

Product Code. 30199606

Brand: Invitrogen™ RP101648

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84321 (PA5-84321. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes the mitochondrial seryl-tRNA synthetase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Specifications

• Accession Number: Q9NP81
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 54938
• Name: Human SARS2 (aa 104-177) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2410015F05Rik; D7Ertd353e; EC 6.1.1.11; mitochondrial seryl-tRNA synthetase; mtSerRS; SARS; Sars2; Sarsm; serine tRNA ligase 2, mitochondrial; serine-tRNA ligase; serine-tRNA ligase, mitochondrial; serine--tRNA ligase, mitochondrial; SerRS; SerRS2; SerRSmt; SERS; seryl-aminoacyl-tRNA synthetase 2; Seryl-tRNA synthetase; seryl-tRNA synthetase 2; seryl-tRNA synthetase 2, mitochondrial; seryl-tRNA synthetase, mitochondrial; seryl-tRNA(Ser/Sec) synthetase; SYS; zgc:66345
• Common Name: SARS2
• Gene Symbol: SARS2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: RSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPD
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining