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Invitrogen™ Human SAP30L (aa 155-183) Control Fragment Recombinant Protein

Product Code. 30206335
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30206335

Brand: Invitrogen™ RP104861

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65525 (PA5-65525. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9HAJ7
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79685
Name Human SAP30L (aa 155-183) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2310079P12Rik; AF006998; DKFZp667L2214; FLJ11526; FLJ23595; FLJ36497; HCV non-structural protein 4 A-transactivated protein 2; Histone deacetylase complex subunit SAP30L; L55; NS4ATP2; SAP30 like; SAP30L; SAP30-like; Sin3 corepressor complex subunit SAP30L; Sin3A associated protein p30-like; sin3A-associated protein p30-like protein; sin3-associated protein p30-like
Common Name SAP30L
Gene Symbol SAP30L
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence KETLAYFIYMVKSNKSRLDQKSEGGKQLE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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