Invitrogen™ Human RGS17 (aa 184-210) Control Fragment Recombinant Protein

Product Code. 30195942

Brand: Invitrogen™ RP105046

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84296 (PA5-84296. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Specifications

• Accession Number: Q9UGC6
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 26575
• Name: Human RGS17 (aa 184-210) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 6430507P11Rik; hRGS17; regulator of G-protein signaling 17; regulator of G-protein signaling Z2; regulator of Gz-selective protein signaling 2; Rgs17; RGS-17; Rgsz2
• Common Name: RGS17
• Gene Symbol: RGS17
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: RDSFPRFLNSQIYKSFVESTAGSSSES
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining