Gibco™ Human Relaxin-2 Recombinant Protein, PeproTech®

Product Code.	Quantity	unitSize
17870683	25 μg	25µg
17831483	100 μg	100µg
17801373	1 mg	1mg
17850493	250 μg	250µg
17890023	500 μg	500µg
17831053	5 μg	5µg

Product Code. 17870683 Supplier Gibco™ Supplier No. 1301525UG

Description

Recombinant Protein

Recombinant Human Relaxin-2 is a non-glycosylated, 6.0 kDa, disulfide-linked, heterodimeric protein consisting of a 24 amino acid A-chain, and a 29 amino acid B-chain. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition. Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus. The gene that encodes the human Relaxin 1 protein maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy. The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.

Specifications

• Accession Number: P04090
• For Use With (Application): Control
• Formulation: Protein with no preservative
• Gene ID (Entrez): 6019
• Molecular Weight (g/mol): 6 kDa
• Name: Human Relaxin-2
• Purification Method: Purified
• Quantity: 25 μg
• Source: E. coli
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/μg
• Gene Alias: bA12D24.1.1; bA12D24.1.2; H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; relaxin 2; Relaxin A chain; Relaxin B chain; relaxin H2; relaxin, ovarian, of pregnancy; RLN2; RLX H2-RLX; RLXH2
• Common Name: Relaxin 2
• Gene Symbol: RLN2
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: A-Chain: QLYSALANKC CHVGCTKRSL ARFC B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.