Invitrogen™ Human REEP5 (aa 59-85) Control Fragment Recombinant Protein

Product Code. 30211648

Brand: Invitrogen™ RP102264

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52016 (PA5-52016. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the parm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Specifications

• Accession Number: Q00765
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 7905
• Name: Human REEP5 (aa 59-85) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AI324241; AU022809; AW495741; C5orf18; D5S346; deleted in polyposis 1; Dp1; DP1/TB2; GP106; polyposis coli region hypothetical protein DP1; polyposis locus protein 1; Polyposis locus protein 1 homolog; Protein TB2; protein TB2 homolog; R74856; receptor accessory protein 5; receptor expression enhancing protein 5; receptor expression-enhancing protein 5; Reep5; TB2; TB2/DP1; Yip2e; YOP1
• Common Name: REEP5
• Gene Symbol: REEP5
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: CNLIGFGYPAYISIKAIESPNKEDDTQ
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining