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STEMCELL Technologies Human Recombinant TGF-alpha
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Quantity:
10 μg
50 μg
Unit Size:
10µg
50µg
Description
- Transforming growth factor-alpha (TGF-α) a member of the epidermal growth factor (EGF) family that is expressed in normal epithelial cells, monocytes, macrophages, brain cells, keratinocytes, and cancer cells
- TGF-α binds EGF receptor (EGFR) and activates tyrosine kinase signaling
- In epidermal and epithelial cells, this results in proliferation and differentiation
- TGF-α is not structurally or genetically related to TGF-β, and the two ligands act through different signaling pathways
- In vitro, TGF-α was shown to stimulate anchorage-independent growth (Singh & Coffey)
Specifications
Specifications
| Name | ETGF, Sarcoma growth factor, TGF, TGF-α, TGF-type I, Transforming growth factor-alpha |
| Quantity | 10 μg |
| Cell Type | Airway Cells; Epithelial Cells; Mammary Cells; Prostate Cells |
| Purity or Quality Grade | ≥95% |
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