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  4. STEMCELL Technologies Human Recombinant Oncostatin M

STEMCELL Technologies Human Recombinant Oncostatin M

Product Code. p-7217618
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Quantity:
10 μg
1000 μg
50 μg
Unit Size:
1000µg
10µg
50µg
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Product Code. 15664959

Brand: STEMCELL Technologies 78094.1

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Description

Oncostatin M

  • Oncostatin M (OSM) is a member of interleukin 6 (IL-6) family of cytokines and bears close resemblance to leukemia-inhibitory factor (LIF) and granulocyte colony-stimulating factor (G-CSF) in amino acid sequence and its modulation of differentiation in a variety of cell types
  • OSM signals through type I receptor (consisting of gp130 and LIF receptor (LIFR)) and type II receptor (consisting of gp130 and OSM receptor (OSMR)), which eventually activate the JAK/STAT pathway
  • OSM is primarily produced by activated T cells and monocytes, and also by activated macrophages, neutrophils, mast cells, and dendritic cells
  • OSM is also produced within the bone microenvironment by cells of both hematopoietic and mesenchymal origin including osteocytes and osteoblasts

Specifications

Name OSM
Quantity 50 μg
Cell Type Airway Cells; B Cells; Hematopoietic Stem and Progenitor Cells; Intestinal Cells; Lymphocytes; Neurons; T Cells
Purity or Quality Grade ≥95%
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