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STEMCELL Technologies Human Recombinant NGF-beta

Product Code. p-7217608
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Quantity:
100 μg
20 μg
Unit Size:
100µg
20µg
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Product Code. 17109551

Brand: STEMCELL Technologies 78092

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This item is not returnable. View return policy

Description

Nerve growth factor beta

  • Nerve growth factor (NGF)-beta is a prototypical member of the neurotrophin family and has a role in the survival and growth of neural cells, regulating cell growth, promoting differentiation into neurons, and neuron migration
  • The beta subtype of NGF is biologically active in comparison to the alpha-2 and gamma-2 subtypes
  • NGF-beta in its secreted form can bind to tyrosine kinase A (TrkA) receptor with high affinity and to p75 (NTR) with low affinity (Levi & Alemà; Sofroniew et al.) NGF has been shown to possess pro-inflammatory and pro-fibrogenic properties (Micera et al.) It has also been shown that overexpression of NGF-beta promotes differentiation of bone marrow mesenchymal stem cells into neurons through regulation of AKT and MAPK pathways (Yuan et al.)

Specifications

Name Beta-nerve growth factor, beta-NGF, nerve growth factor (beta polypeptide)
Quantity 20 μg
Cell Type Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
Purity or Quality Grade ≥95%
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