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STEMCELL Technologies Human Recombinant IP-10 (CXCL10)

Product Code. 17179731
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Quantity:
10 μg
50 μg
Unit Size:
10µg
50µg
This item is not returnable. View return policy

Product Code. 17179731

Brand: STEMCELL Technologies 78165.1

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This item is not returnable. View return policy

Description

Interferon gamma-inducible protein 10

  • Interferon gamma-inducible protein (IP) 10 or CXCL10 is a member of the CXC chemokine family
  • It binds CXCR3 activating ERK1/2, p38/MAPK, JNK, and PI3-kinase/AKT signaling pathways, inducing intracellular calcium influx, DNA synthesis, cell proliferation, and chemotaxis
  • IP-10 regulates innate and adaptive immune responses by affecting the function of activated T cells, natural killer cells, inflammatory dendritic cells, macrophages, and B cells
  • IP-10 is produced by leukocytes, activated neutrophils, eosinophils, monocytes, epithelial cells, endothelial cells, fibroblasts, and keratinocytes in response to IFN-gamma
  • IP-10 has been implicated in a wide range of diseases, including infectious diseases and chronic inflammatory and autoimmune diseases, as well as in tumor formation (Liu et al.)

Specifications

Name 10 kDa interferon-gamma-induced protein, C7, crg-2, Chemokine (C-X-C motif) ligand 10, CXCL10, Gamma-IP-10, gIP-10, IFI10, INP10, mob1, SCYB10, Small inducible cytokine B10
Quantity 50 μg
Cell Type Monocytes; T Cells
Purity or Quality Grade ≥95%
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