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STEMCELL Technologies Human Recombinant IFN-alpha 2B

Product Code. 17159511
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Quantity:
100 μg
20 μg
Unit Size:
100µg
20µg
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Product Code. 17159511

Brand: STEMCELL Technologies 78077

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This item is not returnable. View return policy

Description

Interferon-alpha 2B

  • Interferon-alpha (IFN-α) is a type I interferon, produced by virus infected cells, and is released as a soluble factor to initiate antiviral responses (Isaacs & Lindenmann)
  • IFN-α2 is the most potent IFN-α used in fundamental research and in most clinical applications
  • The best known IFN-α2 subvariants, 2A and 2B, differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (von Gabain et al.) Type I IFNs exert potent antitumor activity by increasing the cytotoxic activity of NK and T cells, as well as inhibiting the proliferation of cancer cells (Paul et al.) Additionally, it has been shown that proinflammatory IFN-α modulates the function of B cells in patients with systemic lupus erythematosus (Chang et al.) and pegylated form of IFN-α 2A and 2B has implications in the treatment of Hepatitis C (Foster et al.)

Specifications

Name IFN-alpha 2, IFNA2, IFNA2b
Quantity 20 μg
Cell Type B Cells; Cancer Cells and Cell Lines; NK Cells; T Cells
Purity or Quality Grade ≥95%
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