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STEMCELL Technologies Human Recombinant IFN-alpha 2B
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Quantity:
100 μg
20 μg
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100µg
20µg
Descrizione
- Interferon-alpha (IFN-α) is a type I interferon, produced by virus infected cells, and is released as a soluble factor to initiate antiviral responses (Isaacs & Lindenmann)
- IFN-α2 is the most potent IFN-α used in fundamental research and in most clinical applications
- The best known IFN-α2 subvariants, 2A and 2B, differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (von Gabain et al.) Type I IFNs exert potent antitumor activity by increasing the cytotoxic activity of NK and T cells, as well as inhibiting the proliferation of cancer cells (Paul et al.) Additionally, it has been shown that proinflammatory IFN-α modulates the function of B cells in patients with systemic lupus erythematosus (Chang et al.) and pegylated form of IFN-α 2A and 2B has implications in the treatment of Hepatitis C (Foster et al.)
Spécification
Spécification
| Name | IFN-alpha 2, IFNA2, IFNA2b |
| Quantity | 100 μg |
| Cell Type | B Cells; Cancer Cells and Cell Lines; NK Cells; T Cells |
| Purity or Quality Grade | ≥95% |
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