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STEMCELL Technologies Human Recombinant Heregulin-beta 1
Description
- Heregulin-beta 1 also known as neuregulin-1 (NRG-1) is a member of the epidermal growth factor (EGF) family of growth factors and acts as a ligand for ErbB family receptor tyrosine kinases
- Heregulin/neuregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3, and NRG4)
- Heregulin-beta 1 plays an important role during the development of the nervous system, heart, and mammary glands
- Heregulin-beta 1 is expressed in neuronal cells, and modulates cell growth and differentiation of the cells during development and wound healing
- It has been implicated through in vivo and in vitro studies that heregulin-beta 1/ErbB signaling is crucial for multiple aspects of cardiovascular development and protects the heart from ischemic injury
- Heregulin-beta 1 also promotes invasiveness and metastasis of breast cancer cells
Specifications
Specifications
| Name | Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin Neu differentiation factor, HRG, HRG1, HRG1-beta 1, Neuregulin-1, NRG1, NRG1-beta 1, Sensory and motor neuron-derived factor |
| Quantity | 10 μg |
| Cell Type | Cancer Cells and Cell Lines; Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons |
| Purity or Quality Grade | ≥95% |
Product Title
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