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STEMCELL Technologies Human Recombinant GDF-11

Product Code. 17119591
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Quantity:
100 μg
20 μg
Unit Size:
100µg
20µg
This item is not returnable. View return policy

Product Code. 17119591

Brand: STEMCELL Technologies 78110

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This item is not returnable. View return policy

Description

Growth differentiation factor 11

  • Growth differentiation factor 11 (GDF-11) is a member of transforming growth factor beta (TGF-β) family
  • It binds to the TGF-β receptors ALK4, ALK5, and ALK7 and activates the SMAD signaling pathway (Ho et al.) GDF-11 regulates the development of the olfactory system, retina, and pancreas, as well as anterior/posterior patterning of the axial skeleton (Lee & Lee)
  • GDF-11 is an endocrine factor expressed in skeletal muscle, brain, and dental pulp (Kondás et al.) Studies in mice showed that GDF-11 regulates muscle and cardiac aging, and stimulates neurogenesis by remodeling blood vessels (Katsimpardi et al.; Loffredo et al.; Sinha et al.)

Specifications

Name BMP-11, Bone morphogenetic protein 11, Growth differentiation factor 11
Quantity 20 μg
Cell Type Neural Cells, PSC-Derived
Purity or Quality Grade ≥95%
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