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STEMCELL Technologies Human Recombinant Fractalkine (CX3CL1)

Product Code. p-7217416
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Quantity:
1000 μg
25 μg
5 μg
Unit Size:
1000µg
25µg
5µg
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Product Code. 17179441

Brand: STEMCELL Technologies 78051

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Description

Fractalkine

  • Fractalkine (CX3CL1) is a unique chemokine belonging to the CX3C family, and is characterized by a C-X3-C cysteine motif within the chemokine domain, near the amino terminus of the protein
  • The chemokine domain is connected to an extended mucin-like stalk, followed by a transmembrane region, and a C-terminal intracellular domain
  • The protein signals through interaction with a single receptor, CX3CR1, expressed on monocytes, natural killer cells, T cells, microglia, and smooth muscle cells
  • Fractalkine is upregulated in endothelial cells by inflammatory signals and is synthesized as a membrane-bound molecule that mediates cell migration and adhesion
  • Cleavage at the base of the stalk by metalloproteinases generates a soluble chemokine, which functions as a potent chemoattractant of target cells

Specifications

Name C3Xkine, Chemokine (C-X3-C motif) ligand 1, FKN, Neurotactin, NTN, NTT, SCYD1, Small inducible cytokine subfamily D member 1
Quantity 5 μg
Cell Type Dendritic Cells; Endothelial Cells; Macrophages; Monocytes; NK Cells; T Cells
Purity or Quality Grade ≥95%
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