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STEMCELL Technologies Human Recombinant FGF-10 (KGF-2)

Product Code. 17149411
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Product Code. 17149411

Brand: STEMCELL Technologies 78037.2

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This item is not returnable. View return policy

Description

Fibroblast growth factor 10

  • Fibroblast growth factor 10 (FGF-10) is a member of the fibroblast growth factor (FGF) family predominantly expressed by mesenchymal fibroblasts during embryonic development (Emoto et al.; Igarashi et al.) It binds with high affinity to fibroblast growth factor receptor 2-IIIb (FGFR2-IIIb), and also has a weaker affinity for FGFR1-IIIb (Beer et al.) FGF-10 and FGF-7 have similar receptor binding properties and target cell specificities but are differentially regulated by components of the extracellular matrix (Emoto et al.; Igarashi et al.) FGF-10 has been shown to mediate epithelial-mesenchymal interactions, which are essential to lung development (Sekine et al; Ware & Matthay)
  • FGF-10 also has a role in mobilization and proliferation of lung-resident mesenchymal stem cells (MSCs) and protection and repair against acute lung injury (Tong et al.; Ware & Matthay), as well as endodermal differentiation of human pluripotent stem cells to insulin-producing pancreatic-like cells (Takeuchi et al.)

Specifications

Name FGFA, Fibroblast growth factor-10, Keratinocyte growth factor-2
Quantity 500 μg
Cell Type Endoderm, PSC-Derived; Hematopoietic Stem and Progenitor Cells; Keratinocytes; Mammary Cells; Mesenchymal Stem and Progenitor Cells; Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Pluripotent Stem Cells; Prostate Cells
Purity or Quality Grade ≥95%
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