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STEMCELL Technologies Human Recombinant CNTF

Product Code. 17129341
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Quantity:
10 μg
50 μg
Unit Size:
10µg
50µg
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Product Code. 17129341

Brand: STEMCELL Technologies 78010

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This item is not returnable. View return policy

Description

Ciliary neurotrophic factor

  • Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that belongs to the four-helix bundle cytokine family and is structurally related to interleukin 6 (IL-6), interleukin 11 (IL-11), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
  • CNTF binds to its receptor CNFTRα and induces formation of a heterodimer of the signal-transducing IL-6 receptor gp130 and LIF receptor (LIFR)-β, which triggers JAK/STAT, ERK, and the PI3K signaling cascades
  • CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders
  • CNTF has also been shown to protect rod photoreceptors from light-induced damage and to have therapeutic effects on retinal degenerative diseases caused by genetic defects or damage induced by toxins, autoantibodies, or strong light

Specifications

Name Ciliary neurotrophic factor
Quantity 10 μg
Cell Type Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
Purity or Quality Grade ≥95%
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