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Invitrogen™ Human RCN3 (aa 94-162) Control Fragment Recombinant Protein

Product Code. 30182100
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30182100

Brand: Invitrogen™ RP99107

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60252 (PA5-60252. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634). [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q96D15
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 57333
Name Human RCN3 (aa 94-162) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 6030455P07Rik; D530026G20Rik; D7Ertd671e; EF-hand calcium-binding protein RLP49; Rcn3; reticulocabin; reticulocalbin 3; reticulocalbin 3, EF-hand calcium binding domain; reticulocalbin-3; RLP49; UNQ239/PRO272
Common Name RCN3
Gene Symbol RCN3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DGWVSLAELRAWIAHTQQRHIRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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