Invitrogen™ Human RBMXL2 (aa 298-320) Control Fragment Recombinant Protein

Product Code. 30201361

Brand: Invitrogen™ RP100851

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62497 (PA5-62497. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

Specifications

• Accession Number: O75526
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 27288
• Name: Human RBMXL2 (aa 298-320) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 1700012H05Rik; Heterogeneous nuclear ribonucleoprotein G; heterogeneous nuclear ribonucleoprotein G T; hnRNP G; hnRNP G-T; HNRNPGT; Hnrnpg-t; HNRPG; HNRPGT; LOC617969 protein; NEWGENE_1598286; RBMX; RBMX like 2; Rbmxl2; RNA binding motif protein, X-linked like 2; RNA binding motif protein, X-linked-like 2; RNA-binding motif protein, x chromosome; RNA-binding motif protein, x chromosome, N-terminally processed; RNA-binding motif protein, X-linked-like-2; testes specific heterogenous nuclear ribonucleoprotein G T; testes-specific heterogenous nuclear ribonucleoprotein G-T; testis-specific heterogeneous nuclear ribonucleoprotein G-T
• Common Name: RBMXL2
• Gene Symbol: RBMXL2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: TPPSYGGGGRYEEYRGYSPDAYS
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining