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Invitrogen™ Human RASGRP3 (aa 590-681) Control Fragment Recombinant Protein

Product Code. 30194345
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30194345

Brand: Invitrogen™ RP110026

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144784 (PA5-144784. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8IV61
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 25780
Name Human RASGRP3 (aa 590-681) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias BC066069; calcium and DAG-regulated guanine nucleotide exchange factor III; calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III; CalDAG-GEFIII; Gm327; GRP3; Guanine nucleotide exchange factor for Rap1; KIAA0846; OTTHUMP00000201245; RAS guanyl releasing protein 3; RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3; RAS, guanyl releasing protein 3; Rasgrp3
Common Name RASGRP3
Gene Symbol Rasgrp3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence AITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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