Invitrogen™ Human PTPN21 (aa 187-267) Control Fragment Recombinant Protein

Product Code. 30207139

Brand: Invitrogen™ RP108627

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84944 (PA5-84944. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PTPN21 (protein tyrosine phosphatase, non-receptor type 21), also known as PTPD1 or PTPRL10, is a 1,174 amino acid member of the PTP family and localizes to both the cytoplasm and the cytoskeleton. Containing one FERM domain and one tyrosine-protein phosphatase domain, PTPN21 functions to catalyze the water-dependent conversion of a protein tyrosine phosphate into a protein tyrosine and a free phosphate and, via this catalytic activity, may be involved in liver regeneration and spermatogenesis. The gene encoding PTPN21 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome.

Specifications

• Accession Number: Q16825
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 11099
• Name: Human PTPN21 (aa 187-267) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21); protein tyrosine phosphatase 2 E; protein tyrosine phosphatase, non-receptor type 21; protein-tyrosine phosphatase 2 E; Protein-tyrosine phosphatase D1; protein-tyrosine phosphatase PTP-RL10; Ptp2E; PTPD1; Ptpn21; PTPRL10; Tyrosine-protein phosphatase non-receptor type 21
• Common Name: PTPN21
• Gene Symbol: PTPN21
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: KVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEGIFVKHKNGRHPVVFRWHDIANMSHNKS
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining