Invitrogen™ Human PSMD11 (aa 164-300) Control Fragment Recombinant Protein

Product Code. 30212604

Brand: Invitrogen™ RP89250

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59933 (PA5-59933. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.

Specifications

• Accession Number: O00231
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 5717
• Name: Human PSMD11 (aa 164-300) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 26 S proteasome non-ATPase regulatory subunit 11; 26 S proteasome regulatory subunit 9; 26 S proteasome regulatory subunit p44.5; 26 S proteasome regulatory subunit RPN6; 26 S proteasome regulatory subunit S9; 2810055C24Rik; C78232; p44.5; proteasome (prosome, macropain) 26 S subunit, non-ATPase, 11; proteasome 26 S subunit, non-ATPase 11; Psmd11; Rpn6; S9
• Common Name: PSMD11
• Gene Symbol: Psmd11
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLA
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining