Invitrogen™ Human PRPF40A (aa 202-264) Control Fragment Recombinant Protein

Product Code. 30194399

Brand: Invitrogen™ RP102820

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58319 (PA5-58319. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.

Specifications

• Accession Number: O75400
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 55660
• Name: Human PRPF40A (aa 202-264) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2810012K09Rik; Fas ligand-associated factor 1; Fas-ligand associated factor 1; FBP11; FBP-11; FLAF1; FLJ20585; Fnbp11; Fnbp3; formin binding protein 11; formin binding protein 3; formin-binding protein 11; Formin-binding protein 3; HIP10; HIP-10; HSPC225; Huntingtin yeast partner A; huntingtin-interacting protein 10; Huntingtin-interacting protein A; HYPA; NY-REN-6; NY-REN-6 antigen; pre-mRNA processing factor 40 homolog A; pre-mRNA-processing factor 40 homolog A; Prp40; PRP40 pre-mRNA processing factor 40 homolog A; PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae); PRP40 pre-mRNA processing factor 40 homolog A (yeast); PRPF40A; Renal carcinoma antigen NY-REN-6
• Common Name: PRPF40A
• Gene Symbol: PRPF40A
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: SQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEI
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining