Invitrogen™ Human Properdin ELISA Kit

Human Properdin quantitates human Properdin in serum, plasma, supernatant.

Product Code	Brand	Quantity
17175159	Invitrogen™ EH383RBX5	5 x 96 Tests
17164683	Invitrogen™ EH383RB	96 Tests

Description

Human Properdin quantitates human Properdin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Properdin.

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.

Specifications

• Accession Number: BCFG; Bf; BFD; C3 Proaccelerator; C3/C5 convertase; cfb; Cfp; Complement factor P; complement factor properdin; GBG; H2-Bf; PBF2; PFC; PFD; PROPERDIN; properdin factor, complement; Properdin P factor, complement
• Assay Sensitivity: 42 pg/mL
• Product Type: ELISA
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene Symbol: CFP
• Intraassay CV: <10%
• Label or Dye: HRP
• Sample Volume: Supernatant, 50 μL; Serum, 50 μL; Plasma, 50 μL
• Target: Properdin
• Total Assay Time: 4 hr 45 min

• Assay Range: 42 to 10,000 pg/mL
• Conjugate: Biotin
• Sample Type: Plasma, Serum, Supernatant
• Gene ID (Entrez): P27918
• Interassay CV: <12%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Regulatory Status: Research Use Only
• Storage Requirements: 2°C to 8°C
• Test Time: 1 hr 20 min