Abnova™ Human PRKCI (NM_002740, 1 a.a. - 587 a.a.) Full-length Recombinant Protein with GST-His tag expressed in Sf9 cells

Used for Func, SDS-PAGE

Brand:  Abnova™ P4760.100ug

Product Code. 16017976

Description

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq]

Specifications

• Accession Number: NM_002740
• For Use With (Application): Functional Study, SDS-PAGE
• Gene ID (Entrez): 5584
• Name: PRKCI (Human) Recombinant Protein
• Purification Method: One-step affinity purification using GSH agarose
• Quantity: 100 ug
• Regulatory Status: RUO
• Common Name: PRKCI
• Biological Activity: 106pmol/μg x min
• Recombinant: Recombinant
• Expression System: Insect cell (Sf9) expression system

• Concentration: 0.369 ug/uL
• Formulation: Liquid
• Molecular Weight (g/mol): 98.027kDa
• Preparation Method: Insect cell (Sf9) expression system
• Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing
• Gene Alias: DXS1179E/MGC26534/PKCI/nPKC-iota
• Gene Symbol: PRKCI
• Species: Baculovirus
• Protein Tag: GST-His
• Form: Liquid