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Invitrogen™ Human PRDM12 (aa 136-209) Control Fragment Recombinant Protein

Product Code. 30180993
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30180993

Brand: Invitrogen™ RP98426

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60257 (PA5-60257. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H4Q4
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 59335
Name Human PRDM12 (aa 136-209) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias Gm998; HSAN8; PFM9; PR domain 12; PR domain containing 12; PR domain zinc finger protein 12; PR domain-containing protein 12; PRDM12; PR-domain containing protein 12; PR-domain zinc finger protein 12; RP11-57C19.7
Common Name PRDM12
Gene Symbol PRDM12
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPDQELLVWYGNSHNTF
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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