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Invitrogen™ Human POU6F1 (aa 108-147) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65617 (PA5-65617. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
Specifications
Specifications
| Accession Number | Q14863 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 5463 |
| Name | Human POU6F1 (aa 108-147) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | 2310038G18Rik; brain-5; Brain-specific homeobox/POU domain protein 5; BRN5; brn-5; brn-5 protein; C79593; cns-1; Emb; MPOU; mPOU homeobox protein; Octamer-binding transcription factor EMB; POU class 6 homeobox 1; POU domain, class 6, transcription factor 1; Pou6f1; TCFB1; transcription regulatory protein MCP-1 |
| Common Name | POU6F1 |
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