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Invitrogen™ Human PON1 Recombinant Protein

Product Code. 11509001
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 11509001

Brand: Invitrogen™ RP75676

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This item is not returnable. View return policy

Description

Recombinant Protein

This product contains purified recombinant human Paraoxonase 1 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P27169
Concentration 0.69 mg/mL
For Use With (Application) Control, Western Blot
Formulation 20 mM tris HCl with 50% glycerol and no preservative; pH 8
Gene ID (Entrez) 5444
Molecular Weight (g/mol) 44.26 kDa
Name Human PON1
Quantity 1 mg
Source E. coli
Regulatory Status RUO
Gene Alias 2810004E20; 6330405I24Rik; A esterase 1; A-esterase 1; A-esterase 2; AI481612; AI786302; Aromatic esterase 1; aromatic esterase 2; arylesterase 1; arylesterase 2; arylesterase 3; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; esterase A; K-45; MVCD5; paraoxanase-3; paraoxonase 1; paraoxonase 2; paraoxonase 3; paraoxonase B-type; paraoxonase nirs; PON; PON 1; PON 2; Pon1; PON2; PON3; serum aryldiakylphosphatase; serum aryldialkylphosphatase 1; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 1; Serum paraoxonase/arylesterase 2; serum paraoxonase/lactonase 3
Common Name PON1
Gene Symbol PON1
Conjugate Unconjugated
Species E. coli
Recombinant Recombinant
Protein Tag His-tag
Sequence Amino acids Met1- Leu355 containing an N-terminal His-tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Protein Subtype Recombinant
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions
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