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Invitrogen™ Human PLCL1 (aa 218-303) Control Fragment Recombinant Protein

Product Code. 30206778
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30206778

Brand: Invitrogen™ RP96032

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56879 (PA5-56879. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q15111
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 5334
Name Human PLCL1 (aa 218-303) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 130 kDa-Ins(1,4,5)P3 binding protein; C230017K02Rik; inactive phospholipase C-like protein 1; p130; phospholipase C like 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; PLCE; PLCL; PLC-L; PLCL1; PLC-L1; PLDL1; PPP1R127; PRIP; PRIP1; PRIP-1; protein phosphatase 1, regulatory subunit 127
Common Name PLCL1
Gene Symbol PLCL1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEF
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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