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Invitrogen™ Human PIASy Synthetic Peptide

Product Code. 15255069
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Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy

Product Code. 15255069

Brand: Invitrogen™ PEP1068

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This item is not returnable. View return policy

Description

Synthetic Peptide

PIAS4 Synthetic Peptide, PEP-1068, from Invitrogen.

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation. [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 51588
Species Human
Purification Method purified
Accession Number Q8N2W9
Common Name Human PIASy
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol PIAS4
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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