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Invitrogen™ Human PDCD2 (aa 57-132) Control Fragment Recombinant Protein

Product Code. 30208579
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30208579

Brand: Invitrogen™ RP108051

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111733 (PA5-111733. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q16342
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 5134
Name Human PDCD2 (aa 57-132) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AI528543; hypothetical protein MGC63685; Pcd2; PDCD2; programmed cell death 2; programmed cell death protein 2; RP8; RP-8; zgc:63685; zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8; ZMYND7
Common Name PDCD2
Gene Symbol Pdcd2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence PLSFLLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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