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Invitrogen™ PD-L2 Human ELISA Kit

Sandwich ELISA Kit

Brand:  Invitrogen™ BMS2215

301.60 GBP valid until 2020-12-18
Use promo code "14718" to get your promotional price.



Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15581727

  • £377.00 / 96 tests


Estimated Shipment
04-12-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human PD-L2

Description

Description

CD273 (PDCD1 Ligand 2, Programmed cell death 2 ligand 2, PD-L2, B7-DC) is involved in cell-mediated immune responses initiated by T lymphocytes that are stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as CD273 that mediate inhibitory signals from the APC (antigen presenting cell). CD273 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; CD273 is specific to the largest isoform. Diseases associated with CD273 include cysticercosis, and myasthenic syndrome.
Specifications

Specifications

Q9BQ51
Biotin
80380
ELISA Kit
3.65 pg/mL
Cell Lysate,10 μL|Plasma, 10 μL|Serum, 10 μL|Supernatant, 10 μL
1 hr. 20 min.
Human
PDCD1LG2, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2
4.5%
Human
HRP
39-2,500 pg/mL
ELISA
Pre-coated 96 well plate, Adhesive Plate Covers, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Controls
RUO
10 μL
2°C to 8°C
3 hr. 30 min.
PDCD1LG2
3.1%
96 Tests
Supernatant
Colorimetric Microplate Reader
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