Invitrogen™ Human PABPC1b (aa 415-441) Control Fragment Recombinant Protein

Product Code. 30202809

Brand: Invitrogen™ RP105419

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66900 (PA5-66900. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

PABPC1b encodes a poly(A) binding protein∣The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs∣The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay∣The gene is part of a small gene family including three protein-coding genes and several pseudogenes

Specifications

• Accession Number: P11940, P29466, P48729, Q8N752
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 122011, 1452, 26986, 834
• Name: Human PABPC1b (aa 415-441) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: pabpc1; poly A binding protein, cytoplasmic 1 b; zgc:77608
• Common Name: PABPC1
• Gene Symbol: PABPC1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: QTQNRAAYYPPSQIAQLRPSPRWTAQG
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining