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Invitrogen™ Human ORAI3 (aa 179-244) Control Fragment Recombinant Protein

Product Code. 30194510
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30194510

Brand: Invitrogen™ RP91115

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82518 (PA5-82518. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

ORAI3 is a protein coding gene that is involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane of cells. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm. ORAI3 has been implicated in a variety of physiological processes, including T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function has been associated with various diseases, including immune disorders, cancer, and cardiovascular disease
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Specifications

Accession Number Q9BRQ5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 93129
Name Human ORAI3 (aa 179-244) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 9930124N15; BC061259; calcium release-activated calcium channel 3; calcium release-activated calcium modulator 3 protein; ORAI calcium release-activated calcium modulator 3; ORAI3; Protein orai-3; RGD1306538; Tmem142c; Transmembrane protein 142 C
Common Name ORAI3
Gene Symbol ORAI3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence APLDTPTPMVPTSRVPGTLAPVATSLSPASNLPRSSASAAPSQAEPACPPRQACGGGGAHGPGWQA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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