Invitrogen™ Human OPA3 (aa 103-168) Control Fragment Recombinant Protein

Product Code. 30182331

Brand: Invitrogen™ RP99016

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60855 (PA5-60855. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: Q9H6K4
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 80207
• Name: Human OPA3 (aa 103-168) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: D630048P19Rik; FLJ22187; FLJ25932; Gm1425; Gm472; MGA3; MGC75494; OPA3; OPA3 outer mitochondrial membrane lipid metabolism regulator; optic atrophy 3; optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); Optic atrophy 3 (Iraqi-Jewish'optic atrophy plus'); optic atrophy 3 protein; Optic atrophy 3 protein homolog; outer mitochondrial membrane lipid metabolism regulator OPA3
• Common Name: OPA3
• Gene Symbol: OPA3
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: RHQLQQRRKEKERRVAREALRGEVGHLGLALEELQAQVQATSTQLALEELRAQLQEVRAHLCLRDP
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining