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Invitrogen™ Human OATP8 (aa 453-478) Control Fragment Recombinant Protein

Product Code. 30208381
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30208381

Brand: Invitrogen™ RP104462

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84034 (PA5-84034. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. The molecular mass of SLCO1B3 is highly dependent on the glycosylation modification (deglycosylated form of 65 kDa, fully-glycosylated form of 120 kDa).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NPD5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 28234
Name Human OATP8 (aa 453-478) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias HBLRR; liver-specific organic anion transporter 2; liver-specific organic anion transporter 3 TM13; LST2; LST-2; LST3; LST-3 TM13; OATP1B3; OATP8; OATP-8; Organic anion transporter 8; organic anion transporter LST-3 c; organic anion-transporting polypeptide 8; SLC21A8; SLCO1B3; solute carrier family 21 (organic anion transporter), member 8; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family, member 1B3
Common Name OATP8
Gene Symbol SLCO1B3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DVPLSYCNSECNCDESQWEPVCGNNG
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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