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Invitrogen™ Human NXPH2 (aa 18-99) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57047 (PA5-57047. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Neurexophilin-1 (also known as NPH1 or NXPH1), Neurexophilin-2 (also known as NPH2 or NXPH2) and Neurexophilin-3 (also known as NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I-alpha (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.
Specifications
Specifications
| Accession Number | O95156 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 11249 |
| Name | Human NXPH2 (aa 18-99) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | neurexophilin 2; Neurexophilin2; neurexophilin-2; NPH2; Nxph2 |
| Common Name | NXPH2 |
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