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Invitrogen™ Human NUMB Synthetic Peptide
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Quantity:
50 μg
Unit Size:
50µg
Description
NUMB Synthetic Peptide, PEP-1257, from Invitrogen.
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
Specifications
Specifications
| Gene ID (Entrez) | 8650 |
| Species | Human |
| Purification Method | purified |
| Accession Number | P49757 |
| Common Name | Human NUMB |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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