Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 2 publications

Product Code	Brand	Quantity
18737389	R&D Systems MAB3771-SP	25 μg
18728498	R&D Systems MAB3771-100	100 μg
18771358	R&D Systems MAB3771-500	500 μg

Description

Neuregulin-1 beta 1/NRG1 beta 1 Monoclonal specifically detects Neuregulin-1 beta 1/NRG1 beta 1 in Human samples. It is validated for ELISA Capture (Matched Antibody Pair).

Specifications

• Antigen: Neuregulin-1 beta 1/NRG1 beta 1
• Dilution: ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
• Gene Alias: ARIA, GGF, GGF2, Heregulin-1, HGL, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1, Neuregulin1 beta 1, NRG1, NRG1-IT2, SMDF
• Gene Symbols: NRG1
• Isotype: IgG1
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

• Clone: 147705
• Applications: ELISA
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: AAA58639
• Gene ID (Entrez): 3084
• Immunogen: E. coli-derived recombinant human NRG1-beta 1/HRG1-beta 1 Ser2-Lys246 Accession # AAA58639
• Primary or Secondary: Primary
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Test Specificity: Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1-beta 1 (amino acids 179-246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177-241). The epitope is present within amino acids 213-230 of human NRG1-beta 1. This segment is present in all NRG1 beta isoforms, GGF-2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha , NDF43, and NRG1-gamma .

For Research Use Only