Invitrogen™ Human Nogo Receptor/Reticulon-4 Receptor ELISA Kit

Product Code. 17125119

Brand: Invitrogen™ EH342RBX5

Description

ELISA

Human Nogo Receptor/Reticulon-4 Receptor quantitates human Nogo Receptor/Reticulon-4 Receptor in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Nogo Receptor/Reticulon-4 Receptor.

NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.

Specifications

• Accession Number: HGNC:1860; NgR; NgR1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo66 receptor; nogo-66 receptor; Nogo66 receptor-1; Nogor; OTTHUMP00000197866; reticulon 4 receptor; reticulon-4 receptor; Rtn4r; UNQ330/PRO526
• Assay Range: 0.85 to 200 ng/mL
• Assay Sensitivity: 0.85 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 65078
• Gene Symbol: RTN4R
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: Nogo Receptor
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins