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Invitrogen™ Human NFRKB (aa 394-513) Control Fragment Recombinant Protein

Product Code. 30197298
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30197298

Brand: Invitrogen™ RP89399

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52384 (PA5-52384. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q6P4R8
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 4798
Name Human NFRKB (aa 394-513) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias A530090G11Rik; DNA-binding protein R kappa B; DNA-binding protein R kappa-B; INO80 complex subunit G; INO80G; NFRKB; nuclear factor related to kappa B binding protein; nuclear factor related to kappaB binding protein; nuclear factor related to kappa-B-binding protein
Common Name NFRKB
Gene Symbol NFRKB
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SLPMLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLWLETKDQAFCKQENEDSSDATTPVPRVRTDYVVRPS
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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