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Invitrogen™ Human NCoR1 (aa 36-60) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
Specifications
Specifications
| Accession Number | O75376 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 9611 |
| Name | Human NCoR1 (aa 36-60) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | 5730405M06Rik; A230020K14Rik; h KIAA1047; hCIT529I10; hN-CoR; KIAA1047; MGC104216; mKIAA1047; NCoR; N-CoR; N-Cor/SMRT corepressor Rip13; N-Cor/SMRT corepressor, Rip13; NCOR1; N-CoR1; nuclear receptor corepressor; nuclear receptor corepressor 1; nuclear receptor co-repressor 1; PPP1R109; protein phosphatase 1, regulatory subunit 109; retinoid x receptor interacting protein 13; retinoid x receptor-interacting protein 13; RIP13; Rxrip13; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1 |
| Common Name | NCoR1 |
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