Invitrogen™ Human NCBP2 (aa 132-156) Control Fragment Recombinant Protein

Product Code. 30212055

Brand: Invitrogen™ RP105232

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66498 (PA5-66498. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: P52298
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 22916
• Name: Human NCBP2 (aa 132-156) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 20 kDa nuclear cap-binding protein; 20 kDa; 5930413E18Rik; AA536802; AI843301; C79367; CBC2; CBP20; cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; NCBP interacting protein 1; NCBP2; NCBP-interacting protein 1; NIP1; nuclear cap binding protein subunit 2; nuclear cap binding protein subunit 2, 20 kD; nuclear cap binding protein subunit 2, 20 kDa; nuclear cap-binding protein subunit 2; phosphatidylinositol glycan anchor biosynthesis, class Z; PIG55; Pigz
• Common Name: NCBP2
• Gene Symbol: NCBP2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: GQVRDEYRQDYDAGRGGYGKLAQNQ
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining