Gibco™ Human Myostatin Propeptide Recombinant Protein, PeproTech®

Product Code. 17861223

Brand: Gibco™ 12012100UG

Description

Recombinant Protein

Recombinant Human Myostatin-Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Mature myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin-Propeptide exhibits high binding affinity for myostatin, and has been shown to be a potent inhibitor of myostatin. Over-expression of myostatin-propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in myostatin knockout mice.

Specifications

• Accession Number: O14793
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 2660
• Molecular Weight (g/mol): 27.8 kDa
• Name: Human Myostatin Propeptide
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: Myostatin
• Common Name: pro-Myostatin
• Gene Symbol: MSTN
• Biological Activity: Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01-0.04 ug/ml in the presence of 50 ng/ml Myostatin.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.