Invitrogen™ Human MT-ND1 (aa 197-218) Control Fragment Recombinant Protein

Product Code. 30211182

Brand: Invitrogen™ RP109116

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140324 (PA5-140324. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer's disease and Parkinson disease.

Specifications

• Accession Number: P03886
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 4535
• Name: Human MT-ND1 (aa 197-218) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: mitochondrially encoded NADH dehydrogenase 1; Mtnd1; MT-ND1; NADH dehydrogenase; NADH dehydrogenase subunit 1; NADH1; NADH-ubiquinone oxidoreductase chain 1; Nd1
• Common Name: MT-ND1
• Gene Symbol: mt-Nd1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: PFDLAEGESELVSGFNIEYAAG
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining