Abnova™ Human MMP8 (447 amino acids ) Full-length native Protein from human blood

Product Code. 16078076

Brand: Abnova™ P4920.10ug

Description

Used for Func, SDS-PAGE

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]

Specifications

• Concentration: 0.2 mg/mL
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: In 50mM Tris-HCl, 200mM NaCl, 5mM CaCl
• Gene ID (Entrez): 4317
• Molecular Weight (g/mol): 75kDa
• Name: MMP8 (Human) Native Protein
• Preparation Method: Native protein purified from human blood
• Purification Method: Affinity Chromatography/Gelfiltration
• Quality Control Testing: 15% SDS-PAGE Stained with Coomassie Blue
• Quantity: 10 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: CLG1/HNC/PMNL-CL
• Common Name: MMP8
• Gene Symbol: MMP8
• Biological Activity: > 20mU/mg
• Species: Human
• Protein Tag: None
• Expression System: Native protein purified from human blood
• Form: Liquid
• Purity or Quality Grade: >95% by SDS-PAGE