Invitrogen™ Human MMP-7 ELISA Kit

Product Code. 17165099

Brand: Invitrogen™ EH328RBX5

Description

ELISA

Human MMP-7 quantitates human MMP-7 in supernatant. The assay will exclusively recognize both natural and recombinant human MMP-7.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.

Specifications

• Accession Number: HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; Mmp7; MMP-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; Pump-1 protease; uterine matrilysin; uterine metalloproteinase
• Assay Range: 0.15 to 100 ng/mL
• Assay Sensitivity: 0.15 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 4316
• Gene Symbol: MMP7
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: MMP7
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins