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Invitrogen™ Human MICALL2 (aa 674-765) Control Fragment Recombinant Protein

Product Code. 30209053
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30209053

Brand: Invitrogen™ RP92856

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55240 (PA5-55240. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth. [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8IY33
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79778
Name Human MICALL2 (aa 674-765) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias JRAB; Junctional Rab13-binding protein; MICAL like 2; MICALL2; MICAL-L2; MICAL-like 2; MICAL-like protein 2; milk2; Molecule interacting with CasL-like 2
Common Name MICALL2
Gene Symbol MICALL2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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