Gibco™ Human MD-2/LY96 Recombinant Protein, PeproTech®

HEK293 cells Recombinant Protein

Brand:  Gibco™ 160-07-50UG

Product Code. 17831753

Description

Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Specifications

• Accession Number: Q9Y6Y9
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 17.2
• Quantity: 50 μg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: LY96
• Conjugate: Unconjugated
• Sequence: QKQYWVCNSS DASISYTYCD KMQYPISINV NPCIELKGSK GLLHIFYIPR RDLKQLYFNL YITVNTMNLP KRKEVICRGS DDDYSFCRAL KGETVNTTIS FSFKGIKFSK GKYKCVVEAI SGSPEEMLFC LEFVILHQPN SNHHHHHH
• Purity or Quality Grade: ≥ 90% by SDS-PAGE gel and HPLC analyses.

• For Use With (Application): ELISA, Functional Assay
• Gene ID (Entrez): 23643
• Name: Human MD-2/LY96
• Source: HEK293 cells
• Regulatory Status: RUO
• Gene Alias: Esop1; ESOP-1; LPS co-receptor MD-2; LY96; ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized