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Gibco™ Human MD-2/LY96 Recombinant Protein, PeproTech®

HEK293 cells Recombinant Protein

Brand:  Gibco™ 160-07-50UG

Additional Details : Weight : 0.16500kg

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Product Code. 17831753

  • £158.00 / 50µg
Estimated Shipment: 12-08-2024
to see stock.

Description

Description

Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Specifications

Specifications

Q9Y6Y9
protein with no preservative
17.2
50 μg
-20°C
<1 EU/μg
LY96
Unconjugated
QKQYWVCNSS DASISYTYCD KMQYPISINV NPCIELKGSK GLLHIFYIPR RDLKQLYFNL YITVNTMNLP KRKEVICRGS DDDYSFCRAL KGETVNTTIS FSFKGIKFSK GKYKCVVEAI SGSPEEMLFC LEFVILHQPN SNHHHHHH
≥ 90% by SDS-PAGE gel and HPLC analyses.
ELISA, Functional Assay
23643
Human MD-2/LY96
HEK293 cells
RUO
Esop1; ESOP-1; LPS co-receptor MD-2; LY96; ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2
Human
Recombinant
Lyophilized
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