Gibco™ Human MD-2/LY96 Recombinant Protein, PeproTech®

Product Code. 17860283

Brand: Gibco™ 16007250UG

Description

Recombinant Protein

PeproTech's HEK293 cell-derived Recombinant Human MD-2/LY96 is a disulfide-linked homodimer whose monomer contains 148 amino acid residues, including a C-terminal His tag, and has a calculated molecular weight of 17.2 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

MD-2 is a gene that encodes a protein involved in the recognition of bacterial lipopolysaccharides (LPS) by the immune system. It is located on chromosome 8 and is part of a larger family of genes that encode for similar proteins. The MD-2 protein forms a complex with Toll-like receptor 4 (TLR4) to recognize and respond to LPS, triggering an immune response. Mutations or variations in the MD-2 gene have been associated with various diseases and conditions, including sepsis and inflammatory disorders.

Spécification

• Accession Number: Q9Y6Y9
• For Use With (Application): ELISA, Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 23643
• Molecular Weight (g/mol): 17.2 kDa
• Name: Human MD-2/LY96
• Quantity: 250 μg
• Source: HEK293 cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: Esop1; ESOP-1; LPS co-receptor MD-2; LY96; ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2
• Common Name: MD-2
• Gene Symbol: LY96
• Biological Activity: Human MD-2/LY96 demonstrates concentration-dependent ability to immobilize rhTLR4 in a functional ELISA
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: QKQYWVCNSS DASISYTYCD KMQYPISINV NPCIELKGSK GLLHIFYIPR RDLKQLYFNL YITVNTMNLP KRKEVICRGS DDDYSFCRAL KGETVNTTIS FSFKGIKFSK GKYKCVVEAI SGSPEEMLFC LEFVILHQPN SNHHHHHH
• Content And Storage: -20°C
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 90% by SDS-PAGE gel and HPLC analyses.