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Invitrogen™ Human LZTR2 (aa 801-885) Control Fragment Recombinant Protein

Product Code. 30197410
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30197410

Brand: Invitrogen™ RP108259

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (60%), Rat (60%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84911 (PA5-84911. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q96JE7
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 89866
Name Human LZTR2 (aa 801-885) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias KIAA1928; Leucine zipper transcription regulator 2; LZTR2; PGPR-p117; protein SEC16 homolog B; protein transport protein Sec16B; Regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein; RGPR; Rgpr-p117; SEC16 homolog B; SEC16 homolog B (S. cerevisiae); SEC16 homolog B, endoplasmic reticulum export factor; Sec16b; SEC16S
Common Name LZTR2
Gene Symbol SEC16B
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence VPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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